Detection & Diagnostics

Detection & Diagnostics

Commercial applications:
> Clinical diagnostics
> Veterinary diagnostics
> Molecular recognition
> Environmental
> Food hygiene
> Decontamination
> Industrial & commercial cleaning

Methods and technology developed to detect and diagnose substances i.e. explosives, chemicals and biological substances across a range of industry sectors and applications.

Brief summaries of our specialist solutions are given below, and you can also download information sheets in pdf format (just enter your email address when prompted to initiate the required document download).

Biomarkers of Traumatic Brain Injury

Traumatic Brain Injury (TBI) can occur when the head receives an impact from a blunt or
penetrating object, or is subject to an injury that causes back and forth movement inside the
skull. The main causes are falls, Road Traffic Incidents (RTIs) and sporting injuries. TBI may
lead to death or permanent disablement.

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Cyclone Bio-threat Detection

Airborne biological threats pose a real and serious concern for both Departments of Defence and the Homeland Security markets.  Threats range from anthrax spores to biological toxins. Current methods to detect their presence are all liquid based (e.g. PCR, immunoassays).  Potential threat agents need to be efficiently extracted from the airborne state for onward liquid-based analysis, a potential threat detected by a “trigger” can then be assessed.

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Humane Rodenticide

The £200m rodenticide manufacturing market is dominated by products based upon anticoagulants.  However, due to issues of concern regarding humaneness, toxicity (resistance) and safety there is increasing pressure upon the industry to develop new products.

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Method for Detection of Target Nucleic Acids Using PCR

Dstl has developed an assay method for detecting the presence of particular nucleic acid
sequences which may be adapted to quantify the amount of the target sequence in a sample.
Using an assay of this type, a fluorescent label becomes incorporated only into the amplification
product allowing delivery of higher specificity and faster detection of target nucleic acids for
methods such as qPCR.

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Population Monitoring

A system for monitoring a live population e.g. for outbreaks of disease and data reporting to a remote station for analysis. For more details: .(JavaScript must be enabled to view this email address)

Pre-symptomatic Determination of Sepsis

Diagnosed cases of sepsis are exceeding 18 million a year and growing at a rate of 8-10% annually with 1,400 patients dying from sepsis each day in the developed world. 
A Dstl team has recently reported the identification of 45 biomarkers which give a predictive accuracy of 97.24% of the onset of the life-threatening, globally occurring condition sepsis, versus baseline comparators, and a 100% predictive accuracy in differentiating sepsis from Systemic Inflammatory Response Syndrome (SIRS).

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Sample Collection using Lateral Flow Strips

A robust and easy to use device has been developed for swabbing surfaces and the sample run on several different lateral flow test strips. A range of materials from explosives to bacterial contamination can be tested for. The sample is retained in the device for subsequent analysis, or as forensic evidence.

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WIBS real time bio-aerosol monitoring

An instrument that can deliver reagent-free, real-time, continuous monitoring of bio-aerosols. This could be used for monitoring of bio-aerosol loads at composting sites, detecting indoor mould spores, environmental research or pharmaceutical clean rooms.

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