Ploughshare Innovations Ltd.
Unit 2, Nine Mile Water Business Park, Nether Wallop, Stockbridge, Hampshire SO20 8DR United Kingdom
T: +44 (0) 1794 301602
© Ploughshare Innovations Ltd 2014
Dstl’s research is held in the highest regard with a worldwide reputation.
> Clinical diagnostics
> Veterinary diagnostics
> Molecular recognition
> Food hygiene
> Industrial & commercial cleaning
Methods and technology developed to detect and diagnose substances i.e. explosives, chemicals and biological substances across a range of industry sectors and applications.
Brief summaries of our specialist solutions are given below, and you can also download information sheets in pdf format (just enter your email address when prompted to initiate the required document download).
Traumatic Brain Injury (TBI) can occur when the head receives an impact from a blunt or
penetrating object, or is subject to an injury that causes back and forth movement inside the
skull. The main causes are falls, Road Traffic Incidents (RTIs) and sporting injuries. TBI may
lead to death or permanent disablement.
Airborne biological threats pose a real and serious concern for both Departments of Defence and the Homeland Security markets. Threats range from anthrax spores to biological toxins. Current methods to detect their presence are all liquid based (e.g. PCR, immunoassays). Potential threat agents need to be efficiently extracted from the airborne state for onward liquid-based analysis, a potential threat detected by a “trigger” can then be assessed.
Dstl has developed an assay method for detecting the presence of particular nucleic acid
sequences which may be adapted to quantify the amount of the target sequence in a sample.
Using an assay of this type, a fluorescent label becomes incorporated only into the amplification
product allowing delivery of higher specificity and faster detection of target nucleic acids for
methods such as qPCR.
Diagnosed cases of sepsis are exceeding 18 million a year and growing at a rate of 8-10% annually with 1,400 patients dying from sepsis each day in the developed world.
A Dstl team has recently reported the identification of 45 biomarkers which give a predictive accuracy of 97.24% of the onset of the life-threatening, globally occurring condition sepsis, versus baseline comparators, and a 100% predictive accuracy in differentiating sepsis from Systemic Inflammatory Response Syndrome (SIRS).
A robust and easy to use device has been developed for swabbing surfaces and the sample run on several different lateral flow test strips. A range of materials from explosives to bacterial contamination can be tested for. The sample is retained in the device for subsequent analysis, or as forensic evidence.
An instrument that can deliver reagent-free, real-time, continuous monitoring of bio-aerosols. This could be used for monitoring of bio-aerosol loads at composting sites, detecting indoor mould spores, environmental research or pharmaceutical clean rooms.