Commercial Opportunities: Biomedical
Remote Monitoring System WO 2001093754 (P1252) Full Details>>
The invention relates to a system for monitoring a live population, with data collected from the population being transmitted to a remote station for analysis. The population, which can be human, animal or plant, is physiologically monitored over time along with location of its members.
The physical condition and location data are sent to a remote data collection computer via telecoms, where they are analysed for unusual events. The data can be reinforced by data from other sources, to predict and highlight unusual events, enabling appropriate action to be taken. The predictive analysis algorithms behind the population/event monitoring system perform more efficiently than manual based systems. The system has been field-tested in a military context.
Clostridium perfringens Vaccines WO 1993023543 (P1102) WO 1997034001 (P1171) Full Details>>
Dstl owns patents on inventions providing recombinant peptides for use as vaccines against both Clostridium perfringens alpha and epsilon toxins, thereby providing prophylaxis or therapy against infections caused by either toxin. C. perfringens is found in soil, dust, faeces, feed and litter. It has been associated with gas gangrene and food poisoning in man, necrotic enteritis (NE) in poultry and various forms of acute enteritis and fatal enterotoxemias in other livestock.
Oral, Nasal & Pulmonary Delivery of drugs and vaccines WO 2000056362 (P1221); WO 2001070200 (P1264); WO 2004062651 (P1349); WO 2006092607 (P1410); WO 2006095176 (P1413) Full Details>>
These patents detail immune stimulation and adjuvant technologies, together with delivery methods, developed by Dstl to facilitate oral, nasal & pulmonary administration of drugs and vaccines.
Bacillus subtilis expression system WO 2003006649 (P1300) Full Details>>
Dstl owns patents on an invention providing recombinant Bacillus subtilis which has been mutated to make it more useful as an in vivo protein expression system. The changes, reducing sporulation, are anticipated to make the B. subtilis strain more efficient at producing proteins.
Stabilisation of Photosensitive Materials (Liposome Technology) WO 1995033448 (P1135) Full Details>>
Drug delivery is an important aspect of the effectiveness of a pharmaceutical. Liposomes can be used to drugs to improve the pharmacokinetics of their delivery within the body. This technology offers a method for stabilising a photosensitive material within a liposome by the inclusion of a photostabilising compound.
The technology offers the added benefit of a lengthened shelf-life, as the photostabilised material may be freeze-dried until required when it can be rehydrated.
Cleaning & Decontamination Fluids WO 2007104971(P1461) Full Details>>
A concentrated cleaning formulation comprising commercially available, biodegradable or environmentally benign constituents has been developed and tested to military decontamination standards. The concentrated “base” fluid provides a phase stabilised microemulsion upon dilution with water (pure or impure) and is ideal for emulsifying water insoluble materials, such as oils, grease, permanent markers and materials thickened with acrylic polymers (such as chemical and biological warfare agents). The diluted fluid solves the problem of effectively removing both water soluble and water insoluble material concurrently from diverse hard surfaces and some porous surfaces. The particular advantage of the product is its ability to have utility across a large array of different applications reducing inventory, logistics and environmental impacts.
